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SKU: 76459781113
Price: 22.96 USD
Availability: InStock
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Description

PT-141 results in increased production of nitric oxide (NO) synthesized from neuronal nitric oxide synthase (nNOS), with the NO activating soluble guanylate cyclase to catalyze the conversion of guanosine triphosphate (GTP, also called guanosine 5'-triphosphate) to cGMP

Considering this, we included all studies that evaluated microglial responses or inflammatory processes following TRPM2 inhibition, either through global or microglia-specific approaches