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(2017) reported that this AChE inhibitory activity is associated with FSE-mediated activation of the Akt/GSK3 pathway, which also led to ameliorated memory and learning difficulties, Al toxicity, AChE hyperactivity, amyloid (A) aggregation, and apoptosis, in rats with AD-like AlCl3induced memory loss in this study

On the other hand, it must be stressed that the above values are averages and there might be significant spatial heterogeneity 57

Supplementary Table 5), reflecting pronounced vascular remodeling and inflammatory responses that may occur following acute hypobaric hypoxia exposure

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