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About obesity Obesity is a serious chronic, progressive, and complex disease that requires long-term management.4-6 One key misunderstanding is that this is a disease of just lack of willpower, when in fact there is underlying biology that may impede people with obesity from losing weight and keeping it off.4,6 Obesity is influenced by a variety of factors, including genetics, social determinants of health, and the environment.7,8 About Novo Nordisk Novo Nordisk is a leading global healthcare company founded in 1923 and headquartered in Denmark

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An additional clinical concern is whether heterogeneous BBB leakage in AD could lead to disproportionate nanoparticle accumulation in regions of increased permeability, thereby increasing the risk of local neurovascular toxicity (Montagne et al., 2020)

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