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While bare AuNPs rely primarily on enhanced permeability and retention (EPR) effects, surface functionalization with polymers like Gum Arabic or bioactive molecules like resveratrol improves tumor specificity and pharmacokinetic profiles [78, 79]

Exposure to pollutants can rarely be totally avoided and, as most of them (ozone, particulate matters, and nitrogen and sulfur oxides, etc.) are pro-oxidants and thus pro-inflammatory, their influence on asthma exacerbations can be partially limited by an administration of anti-oxidant vitamins, which has been described above

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