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Retrieval of the entire Barretts Esophagus segment for histological assessment is ideal, as it may permit referral to surgery for advanced lesions

If reticulocytes have not increased after treatment or if reticulocyte counts do not continue at least twice normal as long as the hematocrit is less than 35%, diagnosis or treatment should be reevaluated

Therefore, targeting Nrf2-related signaling pathways to inhibit ferroptosis has emerged as a promising therapeutic approach for combating central nervous system diseases (Song and Long, 2020)