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Description

Xu J, Su X, Burley SK, Zheng XFS

As an emerging type of luminescent materials, CLgens show uncommon properties, such as non-conjugated structures, clustered emitting species, unmatched absorption and excitation spectra, excitation-dependent emission, and RTP phenomenon

The therapy for this ultra-rare disease uses a similar strategy to Intellias liver-targeting treatments for hATTR and HAE: it consists of a Cas12i2 nuclease and guide RNA encapsulated in a lipid nanoparticle (LNP)