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[82:42] Jared Interesting
Nervous system adverse events Very common (10% or more): Dizziness (12%), drowsiness (10%) Common (1% to 10%): Lightheadedness, decreased concentration, numbness, paresthesia, incoordination, headache, tremor, syncope, seizures Rare (less than 0.1%): Cerebrovascular accident Very rare (less than 0.01%): Serotonin syndrome, amnesia, cogwheel rigidity, dystonia/dystonic reactions, dyskinesias (acute and tardive), ataxias, parkinsonism, akathisia, restless leg syndrome Postmarketing reports : Vertigo, extrapyramidal symptoms, transient difficulty with recall [Ref] Cardiovascular Common (1% to 10%): Tachycardia/palpitations, chest pain Uncommon (0.1% to 1%): Hypotension, hypertension Rare (less than 0.1%): Congestive heart failure, myocardial infarction, cardiomyopathy, bradycardia [Ref] Dermatologic Common (1% to 10%): Rash, sweating/clamminess Uncommon (0.1% to 1%): Pruritus, flushing, easy bruising, hair loss, dry skin, facial edema, blisters Rare (less than 0.1%): Acne, thinning of nails, ecchymosis, urticaria [Ref] Gastrointestinal Common (1% to 10%): Nausea, dry mouth, abdominal/gastric distress, diarrhea, constipation, vomiting Uncommon (0.1% to 1%): Flatulence, anorexia, increased appetite, salivation, irritable colon, rectal bleeding Rare (less than 0.1%): Burning of the tongue [Ref] Musculoskeletal Common (1% to 10%): Musculoskeletal aches/pains Uncommon (0.1% to 1%): Muscle cramps, muscle spasms, rigid/stiff muscles, arthralgias Rare (less than 0.1%): Muscle weakness [Ref] Ocular Common (1% to 10%): Blurred vision Uncommon (0.1% to 1%): Eye redness and itching, conjunctivitis, eye pain, eye pressure, photophobia Very rare (less than 0.01%): Visual changes (including tunnel vision) [Ref] Other Common (1% to 10%): Fatigue, weakness, tinnitus, sore throat Uncommon (0.1% to 1%): Altered taste, altered smell, inner ear abnormality, edema, fever, roaring sensation in the head, malaise Rare (less than 0.1%): Alcohol abuse, loss of voice, hiccoughs [Ref] Psychiatric Common (1% to 10%): Insomnia, nervousness, excitement, anger/hostility, confusion, depression, dream disturbances, attention disturbance, sleep disorder Uncommon (0.1% to 1%): Depersonalization, dysphoria, noise intolerance, euphoria, akathisia, fearfulness, loss of interest, dissociative reaction, hallucinations, involuntary movements, slowed reaction time, suicidal ideation, decreased or increased libido Rare (less than 0.1%): Claustrophobia, cold intolerance, stupor, slurred speech, psychosis, delayed ejaculation, impotence Very rare (less than 0.01%): Depersonalization Postmarketing reports : Emotional lability, restlessness [Ref] Respiratory Common (1% to 10%): Nasal congestion, pharyngolaryngeal pain Uncommon (0.1% to 1%): Hyperventilation, shortness of breath, chest congestion Rare (less than 0.1%): Epistaxis [Ref] Genitourinary Uncommon (0.1% to 1%): Urinary frequency, urinary hesitancy, menstrual irregularity and spotting, dysuria Rare (less than 0.1%): Amenorrhea, pelvic inflammatory disease, enuresis, nocturia Very rare (less than 0.01%): Urinary retention [Ref] Hepatic Uncommon (0.1% to 1%): Increases in hepatic aminotransferases (SGOT, SGPT) [Ref] Metabolic Uncommon (0.1% to 1%): Weight gain, weight loss [Ref] Endocrine Rare (less than 0.1%): Galactorrhea, thyroid abnormality [Ref] Hematologic Rare (less than 0.1%): Eisonophilia, leukopenia, thrombocytopenia, bleeding disturbance [Ref] Hypersensitivity Postmarketing reports : Allergic reactions, angioedema [Ref] References 1
