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Further demonstrating the therapeutic potential of targeting glycolysis, the natural compound derivative D5, sourced from Radix Aucklandiae, attenuates colitis in mice by impeding the nuclear translocation of PKM2 dimers, thereby suppressing glycolytic flux and Th17 cell differentiation (211)

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Lower levels of Igs in cell culture media are preferable to avoid immunological responses and possible interference with cell growth

Funding This study was supported by the Natural Science Foundation of Jiangxi Province (20232BAB216029) and Jiangxi Province Traditional Chinese Medicine Science and Technology Program (2023 A0346)