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We hypothesized that characterization of patients' metabolic profiles, utilizing high resolution 1H-nuclear magnetic resonance (NMR) may predict response to therapy prior to treatment

These concepts were found and developed in subsequent research, although ironically the main innovators, such as Paul Sterling [40] and Bruce McEwen [41], will criticize Selye by attributing to him a static, homeostatic vision

Such deficiencies are associated with worse behavioral and developmental outcomes, including challenges with eye contact, communication, and social interaction

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