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Due to non-selective receptor activity, it also affects multiple physiological signaling systems

The transdermal administration method not only avoids the inconvenience of injection but also provides a more stable blood drug concentration, especially suitable for patients with cardiovascular risks or those with contraindications to oral medications

Microscopic examination of the permanent sections revealed a well-circumscribed, heavily pigmented neoplasm, arranged in nests and composed of epithelioid cells with round nuclei and prominent nucleoli, with admixed melanophages (Figure 3A)