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Description

Oral LT4 is absorbed primarily in the small intestine, particularly in the jejunum and ileum, after dissolution in the stomach

Because of the risk of toxicity, patients with TPMT or NUDT15 deficiency require alternative therapy or dose modification (see DOSAGE AND ADMINISTRATION)

It has been demonstrated to possess a wide range of anti-cancer properties, including anti-proliferative, pro-apoptotic, anti-angiogenic, and anti-metastatic effects