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Suarez C, Miller DR, Steinherz PG, Melamed MM, Andreeff M

Biochem Soc Trans 12:3335 James EA, Gygi SP, Adams ML, Pierce RH, Fausto N, Aebersold RH, Nelson SD, Bruschi SA (2002) Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1, 1, 2, 2-tetrafluoroethyl)-l-cysteine

In contrast, traditional machine learning models such as XGBoost may be more robust and interpretable under small- and medium-sized sample conditions and may be better suited for exploratory deployment in clinical high-throughput data settings

When combining peptides, starting with lower individual doses and gradually adjusting based on response is advisable