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Cells 40 , 503514 (2017)

PLoS ONE 9:e98072 Acknowledgements I wish to thank members of the Rouault lab for their important contributions to insights on mammalian FeS biogenesis, and Nunziata Maio for critically reading this manuscript and making helpful suggestions

Once the system reaches the brain microenvironment, the over-activated microglia secrete MMP-2, which cleaves the Pep-Mino linkage, triggering the controlled release of minocycline