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Clinical evidence remains limited to animal studies, but three decades of research and community experimentation have produced consistent patterns

Any other use may be considered off-label and requires individualized provider evaluation

Acute systemic LPS injections induce pronounced but reversible changes in astrocyte gene expression in the prefrontal cortex, along with an approximate 25% decrease in astrocyte branch and process volumes, but with few currently detectable changes in astrocyte physiology and basic preservation of astrocyte core homoeostatic functions such a potassium buffering

They take a full approach to meet the patients physical and emotional needs