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Although a vitamin B12 overdose is rare, research suggests that some groups of people are at a greater risk of adverse effects from taking an excessive amount of the nutrient

Figure 3: Kaplan-Meier Curves for Overall Survival in Non-Squamous NSCLC in Study JMDB Figure 4: Kaplan-Meier Curves for Overall Survival in Squamous NSCLC in Study JMDB Maintenance Treatment Following First-line Non-Pemetrexed Containing Platinum-Based Chemotherapy The efficacy of pemetrexed as maintenance therapy following first-line platinum-based chemotherapy was evaluated in Study JMEN (NCT00102804), a multicenter, randomized (2:1), double-blind, placebo-controlled study conducted in 663 patients with Stage IIIb/IV NSCLC who did not progress after four cycles of platinum-based chemotherapy

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This could translate to a loss of up to 10-20 pounds for a 200-pound person