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3 Results 3.1 Epidemiology Recent national surveys among Italian adolescents aged 1315 years were prioritized in this review because they provide high-quality, nationally representative data within a well-defined regulatory framework, allowing for a clear interpretation of trends in youth tobacco and e-cigarette use ( Multiple factors contribute to the growing popularity of e-cigarettes among youth (Table 1)

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It also suggests that we need to be more precise when we ask about cigarette smoking frequency. According to Jason Oliver, PhD, assistant professor of psychiatry and behavioral sciences, Duke University, when assessing nicotine addictionclinically referred to as tobacco use disorderclinicians are encouraged to fully assess the 11 criteria listed in the fifth edition of the Diagnostic and Statistical Manual (DSM-5)