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Given the poor bioavailability of oral NAD+ and its precursor vitamins through supplements (and why most wellness supplements have limited benefit), IV or subcutaneous routes are necessary to achieve the serum concentrations observed in the published research

PubMed ID: 3169264 Pickart L & Margolina A (2018) Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of New Gene Data PMC6073405 Gorouhi F & Maibach H (2009) GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration PMC4508379 / PubMed ID: 26236730 Finkley MB et al

Users often notice initial improvements within 2 to 4 weeks

Should a patient become pregnant while using the solution, discontinuation is generally recommended until pregnancy and nursing have concluded