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[PMC free article: PMC42748] [PubMed: 7831299] 203

Heme is formed from succinyl CoA and glycine and is ultimately involved in aerobic metabolism after it is combined with globin chains that are synthesized on the ribosomes in the plasma of the developing erythrocyte

Cell lines Hucct1, RBE, and AML12 cell lines were purchased from Procell with short tandem repeat (STR) identification and cultured in RPMI 1640 (Hucct1 and RBE) with 10% fetal bovine serum or DMEM/F12 (AML12) with 10% fetal bovine serum, 1ITS-G, 40 ng/mL dexamethasone in incubator (37 C, 5% CO 2 )