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For example, Kla at the K147 site of fructose-bisphosphate ALDOA is found in both humans and animals

ROS/oxidative stress signaling in osteoarthritis

As will be discussed later in this review, the primary cellular defense pathway against ferroptosis is the SLC7A11 (p53)GPX4 signaling axis, wherein GPX4 uses GSH as its cofactor to quench lipid hydroperoxides