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Therefore, characterisation of the impacts of different p53 mutant proteins is essential for improving the prognostic and predictive values of mutant p53 for treatment response, as well as for the development of personalised treatments for patients with p53 mutant lung cancers

For example, in one of the spots for Winstons that ran each week during The Beverly Hillbillies, Granny Moses (actress Irene Ryan) put a cigarette from Jed Clampett into the bowl of her corn-cob pipe, took a puff, and exclaimed, My thunder, Jed