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Rutin has also been shown to help microglia uptake extracellular tau oligomers, thereby directly combating AD (253)

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The ACSL4LPCAT3LOX signaling axis is an intracellular pathway known to promote lipid peroxidation of membrane phospholipids (PLs) containing PUFAs and has been identified as one of the components crucial for ferroptosis execution.[34,35,36] We examined the expression of ACSL4 and observed its elevation in stimulated T cells both at mRNA (Suppl