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We also demonstrate that SCLC cells associated with high ASCL1 expression are more susceptible to the blockage of mitochondrial respiratory complex I (NADH dehydrogenase) and, moreover, that non-ASCL1-driven cells are more susceptible to glutaminolysis inhibition, which may allow future subtype-specific personalized therapy

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Low concentrations of nicotinic acid and nicotinamide may be transported by sodium-dependent facilitated diffusion (32) or by proton cotransporters (33) or anion antiporters (34)

MSC transplantation improves cardiac function in MI and reduces cognitive deficits in VCI models