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2019 Jan 23;20(3):490

Mild shoulder soreness is one of the most common side effects of vaccines , affecting 53-83% of vaccine recipients, and typically resolves within 1-2 days (Baden et al, 2021)

The pathophysiology of IC/BPS is poorly understood, and theories include chronic inflammation, autoimmune dysregulation, bacterial cystitis, urothelial dysfunction, deficiency of the glycosaminoglycan (GAG) barrier and urine cytotoxicity