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Metagenomic data indicated that this niche is overwhelmingly dominated by specific bacterial families, particularly Pasteurellaceae and Mycoplasmataceae 97 , which constitute the core commensal landscape (Table 1)

Although the mechanism of PGF2 in RA is unclear, it can prevent cell proliferation, inflammation, tissue remodeling via MMP-3, and angiogenesis via VEGF (147)

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In mice, functional inactivation of the apolipoprotein E gene ( apoE gene) induces athero-susceptibility and apoE / mice develop significant lipid depositions in the arterial wall even when they are maintained on regular low-lipid chow diet (Song et al