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Overexpression of Twist1 and Twist2 in BM-MSCs increased STRO-1 expression (a stemness marker), promoted proliferation and adipogenesis, but inhibited osteogenesis and chondrogenesis, suggesting they help maintain MSC stemness [1]

Roberts JE

A company selling IGF-1 LR3 with testimonials about muscle growth, recovery benefits, or anti-aging effects is distributing an unapproved new drug, even if the label says "not for human consumption." The agency does not require proof of actual human useintent inferred from marketing is sufficient for enforcement