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however, glutathione is significantly depleted in hepatocytes during SNMP, which is probably attributed to the hepatocytes inability to overcome the threshold energy necessary for glutathione synthesis under subnormothermic conditions (145)

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NAC, a direct antioxidant and GSH precursor, inhibits NF-B and other cytokines that contribute to inflammation, which results in the downregulation of many pro-inflammatory genes

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doi: 10.18632/aging.205049 30 KongNChenXFengJDuanTLiuSSunXet al

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Retrieved 2 July 2015

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