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Los genes regulados al alza incluyen aquellos involucrados en la sntesis de protenas de matriz, la respuesta antioxidante y la reparacin de DNA

In contrast, in healthy cells, rhamnetin activates antioxidant pathways such as Nrf2/Keap1, stabilizing mitochondrial function and preventing ROS-induced damage, thereby sparing normal tissues from toxicity [76, 77]