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Gastric tissues were used for microbiological (urease and bacterial count), ELISA (IL-10 and IL-1), gene expression (HIF-1 and TGF-), oxidative stress (TOS, TAS, MDA, CAT, GSH) and immunohistochemical (Hematoxylin and eosin and Giemsa) analyses

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Altogether, the regulation of the HPA axis, plasma CBG levels, and tissue expression of 11-HSD enzymes ultimately determine cortisol bioavailability, which, in conjunction with tissue-specific GR expression and function, dictates the specific biological responses