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Additionally, in Alzheimer's disease models where neuronal dysfunction was induced by intracerebroventricular injection of A 142, treatment with nicotinamide (NAM) effectively prevented memory deficits (210)

Materials and methods Human brain tissue and neuropathology The use of post-mortem brain tissues from the BRAIN cohort (Brain Research in Aging, Inflammation and Neurodegeneration) was evaluated by the METc (nr 2021/496) on August 31, 2021, concluding that the protocol is not clinical research with humans as meant in the Medical Research Involving Human Subjects Act

We, therefore, sorted the metabolic reactions identified by the Compass algorithm into two groups: glycolysis and TCA

10.1073/pnas.0603007103 Proc