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503,504 YAP acts as a redox detector, identified by two regions rich in cysteine, the cysteine-rich domain at the end of the molecule (C-CRD) with redox-responsive Cys598, Cys620, and Cys629 and the cysteine-rich domain at the beginning of the molecule (N-CRD) with Cys303, Cys310, and Cys315

I also wish Browns article had talked more about risks, but it did provide some new insights into the situation and was generally pretty balanced

Luo M, Tian R, Lu N