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Description

Distinct mechanisms of suppression of murine T-cell activation by the related macrolides FK-506 and rapamycin

The mechanisms typically involve chromosomal translocations, aneuploidy, or immunosuppression-induced lymphoproliferation [140, 142]

This combination may interact with antioxidants (such as beta-carotene and selenium), iron supplements (like ferrous sulfate), and anticancer agents (such as cyclophosphamide)