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In contrast, HO emission during state 3 respiration (which most closely resembles the in vivo situation) was unchanged in DM and DM_CKD vs

It remains debatable whether alterations in VHL alone are sufficient to trigger tumorigenic processes in the kidney, especially since experiments failed to detect any tumors in VHL knockout mice (Gnarra et al

ASGPR exhibits specific recognition of structures containing galactose or acetylgalactosamine, thereby offering potential for liver-targeted delivery and reduced systemic toxicity when galactose and acetylgalactosamine-modified drug-carrying nanoparticles or biomacromolecules are utilized

Cells were seeded in complete medium consisting of RPMI-1640 supplemented with 10% FCS (Sigma), 1% Penicillin/Streptomycin (GIBCO), 1% L-Glutamine (Sigma), and 55 mM -mercaptoethanol (GIBCO)