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Kaludov NK, Wolffe AP

FTH1), maintaining GSH balance (cysteine/glutamate transporter

The addition of copper significantly decreased the IC 50 values of disulfiram against acute leukemia cells, slightly increasing the antileukemic activity of the drug (Fig

Several novel TGF-1 receptor kinase inhibitors, including SKI2162 [325], vactosertib (EW-7197) [326], galunisertib (LY2157299) [327] and LY2109761 [328], are demonstrated to specifically block the TGF-1 signaling pathway and hence suppress radiation-induced murine pulmonary and skin fibrosis