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Mitochondrial dysfunction in mouse livers depleted of iron chaperone PCBP1

Symptomatology (i.e., paresthesia, spontaneous pain, tactile allodynia and mechanical and thermal hypo/hyperalgesia) may improve and resolve spontaneously, or culminate in total loss of sensation and ultimately in foot ulceration and amputation

doi:10.1002/prot.340130406 ^ Kern D., Kern G., Neef H., Tittmann K., Killenberg-Jabs M., Wikner C., Schneider G., Hbner G

It is recently determined that chronic alcohol ingestion in experimental animals alters the expression of zinc transporters and causes significant intracellular zinc deficiency in the alveolar macrophage