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In the vaccines clinical trials, it was found that it may cause severe adverse reactions like blood clots and Guillain-Barr syndrome

doi: 10.1021/acscentsci.7b00589 46 YangWSKimKJGaschlerMMPatelMShchepinovMSStockwellBR

Genetic Factors Alteration of the Transsulfuration Pathway One of the classic alterations of the homocysteine metabolism is represented by the homozygous deficiency of CBS (Mudd et al, 1995)