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The research rationale established by NNMT-knockdown studies in diet-induced-obese mice is that inhibiting NNMT preserves intracellular NAD+ and SAM levels, which in adipocyte (fat-cell) models has been shown to suppress de novo lipogenesis

While glutathione is one of the most important antioxidants in our bodies, regular supplementation requires high doses (500-1,000 mg) because most of it gets broken down before reaching cells where it's needed

Zhai S, Zhu Y, Feng P, Li M, Wang W, Yang L, et al

Its protective properties also shield skin cells from damage caused by environmental factors such as UV rays and pollution