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The most informative difference between MES-1 and MES-2 clusters appears to be related to the expression of myogenic markers Myod1, Cdh15 and Peg3 in the cluster of MES-2 myofibroblast: the activation of Myod1 should suppress the connective tissue potential and seal the myogenic fate along with Cdh15, while the expression of Peg3 regulates skeletal muscle lineage commitment and is expressed in both muscle satellite cells and interstitial progenitor cells of non-muscle nature 28

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