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2 Intestinal iron metabolism and regulation As an essential trace element, iron is integral to numerous biological processes, including oxygen transport, ATP production, immune regulation, DNA synthesis, and repair ( 2.1 Intestinal iron absorption and homeostasis The available iron in the body mainly comes from dietary intake and the phagocytosis of senescent red blood cells by macrophages ( + ) at the brush border membrane of epithelial cells

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A., Bierma-Zeinstra, S., Uitterlinden, A