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Nutrients 17 (5), 794

134 Since the initial inflammatory phase is crucial for bone repair, the circadian clocks control over neutrophil activity and aging presents a novel temporal mechanism that could affect the efficiency of bone regeneration

Delving into specific models, T-cell-specific HGK conditional knockout mice (also referred to as T-HGK cKO) with a deficiency in the leptin receptor exhibit reduced Th17 differentiation