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Cisplatin and etoposide combined with the PRMT5 inhibitor GSK3326595 effectively delayed the recurrence of SCLC, suggesting its potential as a promising new drug candidate for delaying SCLC recurrence in patients undergoing chemotherapy

J Psychopathol Clin Sci

The diminished proliferation of gsh2 mutants which are non-melanized and have reduced susceptibility to phagocytosis in the brain of infected mice affirms critical roles for melanin and phagocytic uptake in dissemination (via survival in host macrophages, which can enhance virulence 41 ), traversal of the blood-brain barrier, and neurotropism 7