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Similarly, when BaP was administrated at a dose of 600 mg/kg to the male ICR mice, the genome-wide DNA methylation level in blood and liver followed a downward trend along with the treatment time increasing [160]

As is known, ROS plays a major role in atorvastatin induced oxidative stress ( Furthermore, mitochondrial dysfunction, in particular impaired function of the electron transport chain, is frequently associated with in statin-associated skeletal muscle damage ( GPx4 is the most critical ferroptosis defense gene that encodes cytosolic, mitochondrial, and nucleolar isoforms (Figure 10

DOI: 10.1007/s10989-021-10275-z

Coordination of KSHV latent and lytic gene control by CTCF-cohesin mediated chromosome conformation