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Two-tailed Students t, paired Students t, Mann-Whitney or Wilcoxon tests were used for comparisons between two groups, according to the experimental design and data distribution

Over the past week emails have been exchanged several time a day with the participants all having an input into the content of the emerging guideline

The absolute risk increase for diabetic retinopathy complications was larger among patients with a history of diabetic retinopathy at baseline (semaglutide injection 8.2%, placebo 5.2%) than among patients without a known history of diabetic retinopathy (semaglutide injection 0.7%, placebo 0.4%)