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Increasing evidence suggests that the primary mechanism behind BBB leakage after a stroke is the breakdown of the TJ complex

[5] Source: Spillers NJ, Talbot NC, Luther PM, Ly GH, Roberts CJ, Ahmadzadeh S, Shekoohi S, Viswanath O, Kaye AD

In detoxification pathway, a series of enzyme-catalyzed processes with broad specificities convert the toxic substances into less toxic metabolites by chemical reactions within the body

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