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This result further confirms the involvement of CAR in suppressing the hepatic APR and suggests that its loss-of-function during sepsis contributes to APR induction, possibly indirectly by enhancing plasma IL6 levels

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This leads to visible improvements in skin tightness, reducing the appearance of loose or thinning skin

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Am J Physiol Endocrinol Metab (2012) 302:E108496

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