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10.1002/smll.201905233 Small 111 RimassaL.AssenatE.Peck-RadosavljevicM.PrachtM.ZagonelV.MathurinP.et al (2018)

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In a head-to-head open-label trial reported in February 2026, average weight loss at 84 weeks favored tirzepatide, and the sponsor noted CagriSema did not meet its prespecified non-inferiority target against tirzepatide