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doi: 10.1016/j.biocel.2014.05.016

Outside of clinical studies, to investigate the potential roles of pCBs for the treatment and alleviation of skin diseases and disorders, many types of cell lines have been used in various in vitro studies: inflamed human keratinocytes (HaCaT cells) [29], human SZ95 sebocytes [30], human eccrine-sweat-gland-derived immortalized NCL-SG3 model cells [31], human healthy and stress-induced premature senescent (SIPS) CCD-1064Sk dermal fibroblasts [32], or My-La and HuT-78 cutaneous T-cell lymphoma lines [33]

Gastrointestinal Discomfort: In some cases, individuals using BPC-157 may experience mild gastrointestinal discomfort, such as bloating, nausea, or abdominal pain