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Cureus 12:e11169

However, there is a need to standardize parameter measurements (such as TEWL, collagen density, viscoelasticity, etc.) in randomized, placebo-controlled trials in designs that include estrogen-deficient skin in menopausal women with correlations to biomarkers examined in these clinical studies that assist patients and physicians as to how to evaluate, select, and provide the most effective treatments in the future

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Instead of being a single-receptor agonist, which semaglutide (the drug in Ozempic and Wegovy) is, tirzepatide activates two receptors at the same time