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Future research based on this plant should focus on long-term toxicity studies, dose-response relationships, and the identification of specific toxic compounds and metabolites within kratom as well as after its intake

H 2 O 2 scavenging assay: The catalase (CAT)-like activity of the GSH-CDs (100 g mL 1 ) was evaluated with H 2 O 2 (0.8 M) in neutral sodium acetate buffer solution

However, a study showed similar lymphoscintigraphic changes in patients with lipedema and obesity 41 , limiting its use for differential diagnosis between these conditions

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