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Lipid profile clustering with t-distributed stochastic neighbor embedding (t-SNE) and hierarchical clustering tSNE scatterplots of acquired lipid profiles (for each subject and across all time points) were generated after log2-transformation and z-score scaling using R package Rtsne with perplexity and theta parameters set at 5 and 0.5, respectively 32

21.2 mV in wild-type), fourfold slower inactivation kinetics, and a fivefold increase in persistent sodium current (22.6% vs

Overall, we found the equilibrative transport of compounds to be a widespread phenomenon among the tested transporters and more common than concentrative transport