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Where researchers do add compounds, they are usually pursuing a different axis entirely for example a GH-axis or metabolic peptide for goals KLOW does not target

Toxicology 357 , 2132 (2016)

BaP enters the human body through a series of reactions to form BPDE, which binds to DNA to inhibit the expression of DNMTs, thereby reducing the process of 5mC production and eventually causing a decrease in genome-wide methylation levels [160, 15]